Shingles Presentation

Shingles can be painful and can lead to serious and long-lasting complications1,2

Picture of shingles on back

Shingles presentation 

  • A unilateral, vesicular rash1
  • Causes burning, stabbing, aching, and “shock-like” pain1
  • Some severe cases have been described as worse than labor pain3

Shingles Complications

Postherpetic neuralgia (PHN)

  • Characterized by long-lasting nerve pain that can persist for months (≥90 days), but can sometimes last years1
  • The nature of PHN pain varies from mild to excruciating—approximately half of patients describe their pain as “horrible”1
  • Between 6% and 45% of immunocompromised (IC) patients with herpes zoster developed PHN4,*

*Based on data from a systematic review involving individuals with hematopoietic stem cell transplant, hematologic malignancies, solid tumors, HIV, or solid organ transplants.4

Postherpetic neuralgia (PHN) graphic
Picture of shingles on face

Herpes zoster ophthalmicus

  • Can lead to ophthalmic complications and, in rare cases, blindness1

Disseminated herpes zoster

  • Widespread rash across multiple dermatomes4
  • Most likely to occur in patients who are IC4,5
  • Median occurrence of 3% in patients who are IC4,*
  • Is a marker for varicella zoster virus viremia that can seed the lungs, liver, gut, and brain, and cause pneumonia, hepatitis, encephalitis, and disseminated intravascular coagulopathy1

*Based on data from a systematic review involving individuals with hematopoietic stem cell transplant, hematologic malignancies, solid tumors, human immunodeficiency virus, or solid organ transplants.4

Picture of shingles on neck

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