Reconstitution & Administration
Watch the video and follow the step-by-step instructions to reconstitute and administer SHINGRIX.
SHINGRIX is a suspension for intramuscular administration only.
Vial 1 of 2
AS01B Adjuvant Suspension Component
Cleanse both vial stoppers. Using a sterile needle and sterile syringe, withdraw the entire contents of the vial containing the adjuvant suspension component (liquid) by slightly tilting the vial. Vial 1 of 2.
Vial 2 of 2
Lyophilized VZV gE Antigen Component
Slowly transfer entire contents of syringe into the lyophilized gE antigen component vial (powder). Vial 2 of 2.
VZV=varicella zoster virus; gE=glycoprotein E.
Gently shake the vial to thoroughly mix contents until powder is completely dissolved. The reconstituted vaccine should be an opalescent, colorless to pale brownish liquid.
After reconstitution, withdraw 0.5 mL from the vial containing the reconstituted vaccine and administer intramuscularly. The preferred site for intramuscular injection is the deltoid region of the upper arm.
Prior to reconstitution: Store both the antigen and adjuvant vials between 2° and 8°C (36°and 46°F). Protect vials from light. Do not freeze; discard if frozen.
After reconstitution: Administer immediately or store refrigerated between 2°and 8°C (36° and 46°F). Discard reconstituted vaccine if not used within 6 hours. Do not freeze; discard if frozen.